Lactoferrin Overview

Lactoferrin (LF) ipuroteni yemusango iripo mumukaka mamalia uye kuratidza anti-hutachiona hunhu. Kubva payakatanga kupinda mumakumi matanhatu, pakave nezvidzidzo zvakawanda kusimudzira kukosha kwechirwere cheglycoprotein uye basa rayo mukudzivirira.

Kunyangwe vana vadiki vachigona kuwana chinowedzera kubva mukuyamwa vanaamai vavo, inoshambadzirwa-yakagadzirwa lactoferrin poda inowanikwa kune ese mazera.

1. Chii chinonzi Lactoferrin?

Lactoferrin (146897-68-9) imhando yesimbi-inosunga glycoprotein inemhuri inotapurirana. Mapuroteni aya akapfuma mumasoja ekudzivirira chirwere uye aripo muvanhu nemukaka wemombe. Kunze kwezvo, iwo muhombodo wewakawanda wenyaya wekuvanzika senge misodzi, mateti, mumhino, pancreatic muto, uye bile. Muviri unobva waburitsa glycoprotein mukupindurudza inosimudzira.

Usati waita a lactoferrin Tenga, tora tsamba kuburikidza neiyi tsanangudzo kuti uone kana iyo yekuwedzera yakakodzera.

Huwandu hwehupfumi hwe lactoferrin huripo mu colostrum, ndiyo yekutanga inonamira mvura inoburitswa mushure mekubereka. Iyo yakavanzika mumukaka mukati memazuva maviri kana matatu ekutanga mushure mekubereka. Kunyangwe secretion ye colostrum ichisvika padhuze, huwandu hwakakosha hwe lactoferrin huchiri kuwanikwa mukuchinja uye mukaka wakakura.

Saka, iwe unotora sei lactoferrin kubva bovine colostrum?

Ndibvumire kukutora iwe nenzira yakatwasuka yekuparadzanisa lactoferrin.

Nhanho yekutanga inosanganisira kupatsanura Whey kubva mukaka. Whey ndiyo yemvura byproduct inosara mushure mekuda kana kuwira mukaka uine acidic compound. Iyo yekuzviparadzanisa maitiro inoita kushandisa hydrophobic kudyidzana chromatography uye ion-kuchinjana chromatography inoteverwa nekuteedzana kunotevedzana nemhinduro dzemunyu.

Bovine colostrum inobva kumombe. Iyo yakapfuma mumapuroteni, ma antibodies, mamineral, mavitamini, macarbohydrate, uye mafuta. Aya ma parameter akasimbisa kukosha kwekurapa kwe colostrum, nekudaro, ichikwevera kufarira pakati pevanotsvaga vesaenzi mune yekurapa domain.

Nekuda kwekuti izvo zvirimo zve lactoferrin zvichiderera sezvo nguva yekubereka ichawedzera, nzvimbo yekutsiva inokurudzirwa kumucheche. Tora, semuenzaniso, yakajairika LF pakarepo mushure mekuzvarwa inenge 7-14mg / ml. zvisinei, iyo kokisheni inogona kudonha kusvika kunenge 1mg / ml nemukaka wakakura.

Kana iwe uchida kuzarura mune iyo immunological lactoferrin, iwe unofanirwa kubhengi pane bovine colostrum supplementation.

Inotengeswa-inogadzirwa lactoferrin uwandu hwehupfu chigadzirwa che bovine colostrum. Nekudaro, chigadzirwa icho chave kunetsekana kune vamwe vanhu vanoita sekunge vari kunetseka nekutapukirwa nechirwere chemombe. Zvakanaka, rega ndikuvimbise kuti mamiriro aya haawanzo. Kunze kwezvo, mamwe lactoferrin mucheche anowedzerawo ari maexpista emupunga akagadzirwa geni, mukufarira vanhu vari vasingashiviriri lactose.

Ndedzipi Iwo Iwo Lactoferrin Anowedzera Kubatsira Kune Vakuru Uye Vacheche

2. Nei uchishandisa Lactoferrin Powder seMarongero, iwo maLactoferrin Rubatsiro ari?

Kuchengeta Acne

Cutibacterium uye propionibacterium ine mhosva yeakawanda acne. Lactoferrin inoshanda kurasa aya mabhakitiriya esimbi uye kuderedza mhedzisiro yawo.

Mune mamwe mamiriro, mahara radicals uye anoshanda zvakare oksijeni marudzi anobatsira mukukuvara kwemaseru uye kukuvara kweDNA. Nekuda kwekunetseka kwe oxidative, kuzvimba kunogona kuitika uye kukanganisa kukura kwe acne. Maererano nesainzi yekutsvagisa, lactoferrin inorwisa-oxidant, nekudaro, iko kugona kurwisa emahara radicals.

Kutora lactoferrin padivi pevhitamini E uye zinc kunoderedza acne maronda uye comedones mune angangoita mwedzi mitatu.

Kunze kwezvo, kuzvimba kunokonzeresa kuumbwa kweacne uye cysts nekuvhara iyo mapores. Izvo zvinopesana nekuzvidzivirira kwezve lactoferrin inovimbisa kukurumidza kuporesa kwemaronda.

Dermatologists vanosimbisa pane iyo kuti hutano hwako hwehutachiona chiratidzo cheganda rako. Semuenzaniso, kana gumbo rako remberi richitsemuka kana risina hutano, kushandisa marudzi ese emafuta kumeso kana epasi-mamiriro epasi haagadzirise kuzvimba kweganda, mitambo, kana eczema. Kutora lactoferrin kuchaburitsa hutachiona utachiona husina tsvina mudhirowa nzira ichikurudzira basa reBifidus flora.

Kunze kwekurapa mhezi, lactoferrin yakadzoreredza zviratidzo zve psoriasis uye yakawedzera kukurumidza kupora kubva kumaronda emutsipa wetsono, ayo akapararira pakati pevarwere vane chirwere cheshuga.

Anti-Microbial Mumiriri

Zvidzidzo zvisingaverengeki zvinoratidza kuti Lactoferrin (LN) inodzivirira hutachiona, hutachiona, hutachiona, uye hutachiona hwehutachiona kurwisa muviri. dhata yacho inoshanda nekusunga kune hutachiona uhu, kudzikamisa chimiro chavo chemasero, uye kuvharidzira ma cell receptors.

Mune imwe fundo, vesaenzi vakacherekedza izvozvo lactotransferrin (LTF) yaive yakanyanya kushanda pakudzivirira herpes hutachiona kupfuura shanduro yevanhu. In vitro zvidzidzo zvakare zvinoratidza kuti iyi yekuwedzera inoshanda nemazvo mhedzisiro yehutachiona.

Mune zvishoma yepamusoro dosi, lactoferrin inoshanda kubata hutachiona hweHepatitis C. Zvinoenderana Hepatology Research, uku kurapa kunowedzera kutaura kweiyo interleukin-18, puroteni inotungamira nekudzosa hutachiona hweHepatitis C. Kuti uwedzere kushanda zvakanaka, varwere vanofanirwa kutora anenge 1.8 kusvika 3.6 magiramu ehuputi pazuva. Icho chikonzero ndechekuti yakadzika dosi ye lactoferrin haizoiti mutsauko mune yehutachiona.

Pane fungidziro, idzo dzinoona seLF kurapwa kwehutachiona hwe helicobacter pylori. Paunenge uchipfekera chiwedzerwa neicho marapirwo ako ekurapa maronda, mikana ndeyekuti mishonga yacho ive inonyanya kushanda. Ichi chikumbiro chave chiri kukakavara kwepfupa pakati pevaongorori sezvo vazhinji vanobata kuti lactoferrin poda inoshandiswa ichave isingaonekwe mukushayikwa kwemishonga yekunyora.

Kutongwa kweIron Metabolism

Lactoferrin haingori chete kudzora kusunganidzwa kwesimbi mumuviri asi zvakare kuwedzera kuwedzera kwayo.

Pave paine kuenderera mberi kwekiriniki kuongororwa uko kwakatsvaga kuenzanisa nekubudirira kweLF kurwisa ferrous sulfate mu iron kushaya anemia panguva yekuzvitakura. Eya, kubva mukuedzwa, lactoferrin yakaratidza kuve yakasimba mune kukurudzira kuumbwa kwehemoglobin nemasero matsvuku eropa.

Vakadzi vanodya glycoprotein vane akakwana masimbi esimbi ane zero mativi. Lactoferrin inoshanda kuti uderedze mikana yekukanganisa, kuberekwa kwepamberi, uye yakaderera kuberekwa.

Naizvozvo, zviri pachena kuti chinhu chakanakira amai vanepamuviri uye vakadzi vezera rekubereka mwana vanorasikirwa nemamwe ma irons kana vari mumaments avo. Vegetarians uye vanowanzo kupa vanopa vangabatsirwawo ne lactoferrin supplements.

Hutano hweGastrointestinal Turakiti

Lactoferrin mucheche inowedzera detoxifying uye inoita gut iine hutano. Inobvisa mabhakitiriya anokuvadza, ayo ane mhosva yekuzvimba. Semuenzaniso, hutachiona uhwu hunopa huwandu hwenyaya dzegastroenteritis kesi uye enterocolitis, inokuvadza matumbo echibereko inotungamira kurufu rwekukurumidza. Kana nekuda kwechimwe chikonzero, mwana wako asiri kuyamwa, zvinokurudzirwa zvakanyanya kuti utendeukire ku bovine lactotransferrin (LTF).

Ndedzipi Iwo Iwo Lactoferrin Anowedzera Kubatsira Kune Vakuru Uye Vacheche

3. Lactoferrin Inobatsira pane Mucheche

Lactoferrin mucheche yekuwedzera inokanganisa kukura kwehutachiona mumukati mevacheche vachangozvarwa. Hutachiona uhu hunosanganisira Escherichia coli, Bacillus stearothermophilus, Staphylococcus Albus, Candida albicans, uye Pseudomonas aeruginosa. Zvidzidzo zvinoverengeka zvinotsigira chokwadi chekuti kudya kwemazuva ese kwealactoferrin yakawanda inowedzera kunoderedza mikana yevasoviral gastroenteritis muvacheche.

Ndichiri mudumbu, LF inosimudzira kuwanda kwemasero endothelial apa ichitaura kukura kweelmphatic follicles. Naizvozvo, zvinova pachena kuti lactoferrin supplementation inogona kunge iri mishonga yekukuvara kwamatumbo mucous.

Kuyamwisa ndiko kunonyanya kupa simbi neonates. Nekudaro, vana chiremba vezera vanokurudzira kuti kuwedzerazve kuwedzera kwesimbi kuri madikanwa sezvo mukaka wamazamu uine mashoma emari iyi.

Nditendere kuti nditsanangure kuti nei LF chiri chinhu chakanakira kuwedzera kuvacheche uye vacheche vanozvarwa vaine hushoma hwekuzvara. Kazhinji, iri boka rinokurirwa zvakanyanya neasalt-kushomeka anemia. Kutungamira iyo lactoferrin yekuwedzera mwana mucheche kunowedzera hemoglobin nemasero matsvuku eropa mushezi yemwana mudiki. Uyezve, ongororo dzinoratidza kuti iron yekuwedzera inowedzera kukura kwemutsipa mucheche.

Dzimwe nguva, mabhakitiriya anokuvadza senge E.coli anodyira pane iripo simbi pane neonatal ematumbo ematumbo. Kutora lactoferrin kuchanyima hutachiona hwevhu uye kuvaparadza asi uchiona kuti mupi anogamuchira zvese zvicherwa zviripo.

LF inoita basa rakakura mukukudziridza kwemuviri wemuviri immune system. Mamwe eaya anoshandiswa lactoferrin poda anosanganisira kuwedzera kwebasa re macrophages, immunoglobulins, NK masero, uye T lymphocyte, ayo anotarisana neonatal immune. Chii chimwezve, kupa LF kunoderedza kushungurudzika kune allergener.

4. Lactoferrin Inovandudza Sei Mumuviri Muviri?

Mediates pakati peAdaptive uye Innate Immune Mabasa

Kune mhinduro yekudziya kwemukati, lactoferrin inoshanda munzira dzinoverengeka. Semuenzaniso, iyo inosimbisa zviitiko zveasipo emhondi masero (NK) uye neutrophils. Iyo protein inowedzera phagocytosis uye inokonzera kuwedzera kwemacrophages.

Yemhinduro inoshanduka, LF inobatsira mukushandurwa kweT-masero uye B-masero. Panyaya yekusagadziriswa kwekusaina, zvese zviri mukati uye zvinoshanda zvemuviri zvinoshanda zvinosangana kuti zvisanganisike.

Lactoferrin inogadzira kugadzirwa kwe-pro-immune cytokines uye interleukin 12, iyo inoratidza zvinodzivirira zvivakwa zvinopesana nehutachiona hwehutachiona hwehutachiona.

Mediates mune yeSystemic Kufuridzira Kupindura Syndrome (SIRS)

Basa re lactoferrin poda mukudzvinyirira iyo reactive oxygen marudzi (ROS) kwave kuri zvakakosha mukudzidza hukama hwayo nekuzvimba nekukura kwekenza. Kuwedzera kweROS kunoshandura kune njodzi dzakakwirisa dzekushungurudzika mamiriro nekuda kweapoptosis kana kukuvara kwenhare.

Kudzivirirwa Pakutsigira Microorganisms

Izvo zvinorwisa-hutachiona zvinokuvadza zve lactoferrin zvinotemwa pamabhakitiriya, hutachiona, hutachiona uye hutachiona hwefungus.

Microbes inobudirira uye inoenderana nesimbi kukura uye kupukunyuka. Kana ivo vakapinda murwi, LF inodzikisira yavo kushandiswa kwesimbi.

Munguva yekutanga kwehutachiona, lactoferrin (LF) inopinda kuti igadzirise kukurudziro yekune dzimwe nyika munzira mbiri dzakajeka. Mapuroteni acho anogona kuvharidzira cellular receptors kana kusungira kuhutachiona, nekudaro, ichidzivirira kupinda kwayo muhomwe. Zvimwe zvinopesana nehutachiona-zviitiko zve lactoferrin zvinosanganisira kukanganisa hutachiona nzira yeiyo pathogen kana kuvharidzira yavo carbohydrate metabolism.

Zvidzidzo zvinoverengeka zvinokonzeresa lactoferrin powder inoshandisa mukutarisira kwehutachiona hweHyppes, hutachiona hweHIV, Hempatitis C neB, furuwenza, uye hantavirus. Kunze kwezvo, iyo yekuwedzera yakadzivirira kuwedzera kwe alphavirus, rotavirus, papillomavirus yevanhu, uye nevamwe vanoverengeka.

Mune zvimwe zviitiko, Lactoferrin inogona kusaburitsa hutachiona hwese asi unogona kuva nechokwadi chekuti ichadzora kudzikama kwehutachiona huripo. Mune zvidzidzo zvakapfuura, LF yaive yakabatsira pakumisa iyo SARS pseudovirus. Sezvo SARS-CoV-2 inowira mukirasi imwechete seSARS-CoV, pane mukana wekuti lactoferrin inogona kuderedza iyo virulence yeCOVID-19.

Kunyangwe menduru dzichibata kuti kuwedzera simba rako rekudzivirira muviri kusinga chengetedze imwe kubva ku coronavirus, lactoferrin supplementation ichabatsira muhondo. Mushure mezvose, ivo varapi vakafanana vakaona kuti vakweguru uye vanhu vanekudzivirira kwakaderera vari panjodzi huru yekubatwa neCOVID-19.

5. Lactoferrin Powder Vanoshandisa uye Kushandisa

Lactoferrin yakawanda yakawandisa poda inowanikwa yekutsvaga masayendisiti uye nyanzvi dzinoda kusimudzira kukosha kwadzo pakurapa pane muviri wemunhu. Iyo ine tarisiro yakawanda yekushandisa mukudzivirira kwechirwere, hutano hwekuwedzera, chikafu uye mishonga antiseptics, uye cosmetics.

Kune kwako kuongorora uye kuedza kwemahebhu, simbisa kuti unotora sosi kubva kune vanoshanda lactoferrin powder suppliers.

Lactoferrin poda shandisa mukati mucheche mukaka hupfu

Mwana mucheche ufa formula inoramba ichienderera kusvika pakuratidzira iyo biochemistry yemukaka chaiwo wemazamu kubva kuna amai. Lactoferrin ndiyo huwandu huviri hwakawanda hwehupfumi mumukaka wamayi weamai. Iyo yakakurumbira kuunza marudzi ese ezvibatsiro kumwana kusanganisira kusungira simbi yekudzivirira, kudzivirira cancer, nekusimudzira mapfupa ane hutano pakati pevamwe.

Lactoferrin chimwe chikamu chakakura mukaka mamai wekutanga unozivikanwa se colostrum. Colostrum ine zvakapetwa zvakapetwa zvakapetwa nekaviri pamililita kunge mukaka wamazamu wakakura. Izvi ndezvekureva kuti vacheche vadiki pane vese vanoda chinhanho chepamusoro che lactoferrin yekukura kwakanyanya.

Kuvandudzwa musimba remucheche immune system inotsigirwa neLactoferrin chikamu mune mucheche mucheche. Mapuroteni anoita basa rakakosha musimba remucheche immune system uye anomiririra yekutanga anti-hutachiona uye inodzivirira-hutachiona hwehutachiona. Iyo yakakosha anti-microbial maitiro inonyanya kuunzwa nezve-iron-ions chelation, izvo zvakakosha pakukura kwebhakitiriya. Kunze kwezvo, lactoferrin inofungidzirwazve kuita seantioxidant iyo inogona kusimbisa kupindirana kwemuviri nekugonesa kusiyanisa, kuwedzera, uye kuvandudza kwemaseru emuviri.

Ndedzipi Iwo Iwo Lactoferrin Anowedzera Kubatsira Kune Vakuru Uye Vacheche

6. Lactoferrin Side Mhedzisiro

Kuchengetedza kweLF pivots pane zvishoma zvinhu.

Lactoferrin uwandu hwemadhidhi madhidhizi anogona kuve echaya. Semuenzaniso, kana supplement yacho ichibva mukaka wemombe, iwe unogona kuishandisa zvine chivimbo kuti yakakwira yakawanda kwegore. Nekudaro, kana chigadzirwa ichi chichibva mupunga, mikana ndeyekuti zvinoteedzana kuwanza kwemavhiki maviri zvichaburitsa humwe hukasha.

Typical lactotransferrin (LTF) mhedzisiro inosanganisira;

  • Diarrhea
  • Kufirwa kwechido
  • Ganda rinoputika
  • Constipation
  • Chills

Kusiyana nemishonga yakawanda inowedzera, lactoferrin yakachengeteka kutarisira uye kuyamwisa mama.

Kupfuudza lactoferrin mhedzisiro, mutengo wepakati pe200mg kusvika 400mg unokurudzirwa. Iwe unofanirwa kuitora kwemwedzi miviri kusvika mitatu inoteedzana. Muzviitiko zvisingawanzo, iyo nguva inogona kukwira kusvika kumwedzi mitanhatu.

7. Ndiani anogona Kubatsirwa neLactoferrin?

Maternal

Lactoferrin inobatsira vese amai nemwana.

Munguva yekuenda kumwedzi, kupa ichi chinyorwa kunogona kuve nechinobatsira pahukuru hwe fetus uye huremo hwayo hwekuzvarwa. Kana amai vakaenderera ne lactoferrin dosage panguva yekuzvitakura, gadziriso yavo yemukaka wemazamu ichavandudza zvakanyanya. Kunze kwezvo, mucheche aizozvirumbidza nenzira isina kunamatira mu colostrum yekuchengetedza hutano hwemuviri.

Vacheche uye Vacheche Vacheche vasina kuyamwiswa kana Kusanganiswa

Iyo lactoferrin inowedzera inovimbisa kuti mucheche anovandudza immune system asi achidzivirira gomarara remudumbu kubva kune allergener. Kunze kwezvo, iyo yekuwedzera inoshanda senge maricho, ichibatsira mukutanga mudumbu kufamba kwemucheche. Vacheche mafomasi akapfuma mu colostrum anowanikwa kubva kune epamusha uye epamhepo Lactoferrin powder suppliers.

Kushaikwa kwesimbi Anemia

Lactoferrin inowedzera zvakanyanya huwandu hwehemoglobin, masero matsvuku eropa, uye ferritin. Kunyangwe vanhu vazhinji vachishandisa ferrous sulfate kupikisa kushomeka kwesimbi, zvakawanda zviongororwa zvidzidzo zviri kuratidza kuti lactoferrin ine simba zvakanyanya.

Kana iwe uri wemakwenzi kana anowanzo kupa muropa, iwe unoda zvikafu zvine iron-simbi kuti zviitire yakaderera hemoglobin uye ferritin mazinga. Kana zvisina kudaro, iwe unogona kugadzira lactoferrin yakanaka kutenga kubva online vatengesi.

Vanhu vane Low immune

Lactoferrin inodzivirira muviri kubva kuzvipembenene nekuvhara hutachiona uye kutadzisa kuwanda kwehutachiona uye hutachiona. Iyo yakakomberedzwa inoshingairira mukushandurwa kwemasaini ekusaina nzira dzakatarisana nekutarisa mhinduro dzehutachiona dzemugamuchiri.

Lactoferrin inoshanda semurevereri, kuvharira nekurongedza mashandirapakati ari pakati pezvinhu zvinoshanda zvemuviri uye zvemuviri. Semuenzaniso, inovandudza phagocytic zviitiko nekukwira kweiyo neutrophils uye macrophages. Kune immune system inoshanda, ino inomhanyisa kukwidziridzika kweT-masero uye B-masero, anoratidza masero-ari pakati uye anonyadzisa kusadzivirira, zvichiteerana.

8. Lactoferrin ine IgG

Sezvakangoita lactoferrin, IgG kana kuti immunoglobulin G ipuroteni inodzivirira-hutachiona mumukaka memamalia.

Ongororo dzinoverengeka dziripo kutsanangura kuenderana pakati pe lactoferrin uye IgG.

Iko kusunganidzwa kwe lactoferrin mu colostrum kwakanyanya kwakanyanya kupfuura iko kweIgG. Maererano nesainzi yekutsvaga, zvinhu zvinoverengeka zvinokanganisa huwandu hwemapuroteni aya mumukaka.

Semuenzaniso, ese ari maviri lactoferrin uye IgG anoterera kupisa uye pasteurization. Immunoglobulin G inogona kutsungirira kupisa kurapa kusvika kusvika 100 ° C asi isina kana masekondi mashoma. Asi zvinopesana, lactoferrin inoderera zvishoma nezvishoma nekuwedzera kwekushisa kusvikira yanyatsopera pa100 ° C.

Kubhadhara pane aya mapepa, unofanirwa kunge wakaziva kuti nguva nekudziya kupisa ndiko kufunga kukuru kana uchigadzirisa mukaka unonatal. Sezvo mukaka pasteurization waiswa pasi pekukakavara, vanhu vazhinji vanogadzirisa kuoma-kutonhora.

The they Lactoferrin (146897-68-9) iri panguva yayo yepamusoro mushure mekubereka. Sezvo nguva yepashure inowedzera, protein iyi inoderera zvishoma nezvishoma, pamwe nekuda kwekuderera kwe colostrum. Kune rimwe divi, kudonha mumazinga e immunoglobulin G ingangoita isingagoneki munguva yose yekubereka.

Nekudaro yakawanda lactoferrin inodonha mumukaka wamamalia, kusimbisa kwayo kuchiri kwakakwira kupfuura iko kweIgG. Chokwadi ichi chinoramba chakamira nyangwe iri mu colostrum, ichichinja, kana mukaka wakura.

References

  • Yamauchi, K., et al. (2006). Bovine Lactoferrin: Zvakanakira uye Mechanism Yekuita Kurwisa Utachiona. Biochemistry uye Cell Biology.
  • Jeffrey, KA, et al. (2009). Lactoferrin seye Natural Natural Immune Modulator. Dzazvino Mishonga Dhizaini.
  • Lepanto, MS, et al. (2018). Kunyatsoita kweLactoferrin Oral Administration mune Kurapa kweAnemia uye Anemia yekuzvimba mukati mevakadzi vane Pamuviri uye Vasiri Vepamuviri: Chidzidzo chekupindirana. Mitsva mu Immunology.
  • Goldsmith, SJ, et al. (1982). IgA, IgG, IgM uye Lactoferrin Zviri Mukati yeMukaka wevanhu Munguva Yekutanga Lactation uye Mhedzisiro Yekugadzirisa uye Kuchengetedza. Chinyorwa chekudzivirira Kwekudya
  • Smith, KL, Conrad, HR, uye Porter, RM (1971). Lactoferrin uye IgG Immunoglobulins kubva kuInngenor Bovine Mammary Glands. Chinyorwa cheDairy Science.
  • Sanchez, L., Calvo, M., uye Brock, JH (1992). Biological Basa reLactoferrin. Archives eChirwere muUcheche.
  • Niaz, B., et al. (2019). Lactoferrin (LF): A Natural Anti-Microbial protein Yenhabvu Yenyika Dzese dzeChikafu Zvivakwa