NMN upfu (1094-61-7)

October 30, 2018
SKU: 1094-61-7

Raw Nicotinamide Mononucleotide (NMN) hupfu hwakadzvanywa nezera-rinosangana nehuremu hwemuviri kuwedzera…


Mamiriro: MuMitambo Yokugadzira
Unit: 25kg / Drum
Unyanzvi: 1370kg / mwedzi

Nicotinamide Mononucleotide (NMN) (1094-61-7) vhidhiyo

Raw Nicotinamide Mononucleotide (NMN) powder (1094-61-7) Tsanangudzo

Raw Nicotinamide Mononucleotide powder ("NMN" uye "β-NMN") inonzi nucleotide inobva ribose uye nicotinamide. Kufanana ne nicotinamide riboside, NMN inobva kune niacin, uye vanhu vane enzyme dzinogona kushandisa NMN kuunza nicotinamide adenine dinucleotide (NADH).

Nemhaka yokuti NADH inobatanidza miitiro mukati me mitochondria, nokuda kweiritiin, uye nePARP, NMN yakadzidzwa mumhuka yehutano seanokwanisa kuita neuroprotective uye anti-old aging agent. Zvokudya zvinowedzera makambani akashandisa zvekutsvaga mararamiro eNMN achireva izvozvo, kunyange pasina kliniki yekudzidza pamusoro pevanhu yakabudiswa zvakadaro.

 

Raw Nicotinamide Mononucleotide (NMN) powder (1094-61-7) Tsanangudzo

Product Name Raw Nicotinamide Mononucleotide (NMN) powder
Kemikari Name Beta-nicotinamide ribose monophosphate; Raw Nicotinamide Mononucleotide powder; AC1Q6RVF; AC1L23AN; NMN (+); SCHEMBL6858129
muchiso Name Mirailabo
Kirasi yeMishonga Dietary supplement
CAS Number 1094-61-7
InChIKey DAYLJWODMCOQEW-TURQNECASA-N
Molecular Formula C11H15N2O8P
Molecular Wsere 334.22
Monoisotopic Mass 335.229 g / mol
Kunyorera Point  > 96 ° C
Freezing Point Hapana zuva rawanikwa
Biological Half-Life Nokudaro, sezvinoratidzwa muFiani 3, nicotinamide yakanyangarika kubva muropa nehafu yeupenyu hwemaawa 5.3, asi hafu yeupenyu ye nicotinic acid yaiva 1.1 awa.
ruvara Yakachena kune off-chena poda
Skukodzera  Methanol (Zvishoma), Mvura (Zvishoma)
Storage Temperature  Hygroscopic, -20˚C Freezer, In Iner Atmosphere
APane Kuti uite basa rekuwedzera upenyu nekurapa chirwere cheshuga

 

Raw Nicotinamide Mononucleotide (NMN) powder (1094-61-7) Tsanangudzo

Raw Nicotinamide Mononucleotide powder ("NMN" uye "β-NMN") inonzi nucleotide inobva ribose uye nicotinamide. Kufanana ne nicotinamide riboside, NMN inobva kune niacin, uye vanhu vane enzyme dzinogona kushandisa NMN kuunza nicotinamide adenine dinucleotide (NADH).

Kutsvakurudza kutsva kunoratidza kuti NMN inogona kudzorera masero emagetsi, uye ine zvinopesana nezvinokanganisa kukwegura. Kuitika kwomuviri mumuviri, NMN (β-Nicotinamide mononucleotide) inokosha kuti kutendeuka kwezvinhu zvive nesimba. Kuwedzera NMN sechikamu chehurumende yako yezuva nezuva kunogona kupa simba revitalisation, kudzivirirwa kubva pakukwegura, uye kuderedza ngozi yehutano hwemwoyo. NMN inobatanidza muitiro redox, chirongwa chakakosha kumagadzirirwo emagetsi ekuumbwa kweAATP yepamusoro-simba yekupa molecule. NMN ine Sirtuin activating compound iyo inokurudzira kushandiswa kwemagetsi uye kurarama kwenguva refu.

Kushandisa Nicotinamide Mononucleotide (NMN) powder (1094-61-7)

  1. Nicotinamide mononucleotide mumasero evanhu anoita basa rinokosha mukugadzira simba, rinobatanidzwa muNAD inopellular (nicotinamide adenine dinucleotide, cell energy conversion inokosha coenzyme) synthesis, inoshandiswa mukurwisana nekukwegura, kuwira shuga yeropa uye nemimwe michina yekuchengetedza utano.
  2. Nicotinamide Mononucleotide is vitamin inogadzika mumvura, Chigadzirwa chichena chekristalline powder, chisina kunaka kana chinenge chisina kunaka, chinorwadza mukudya, chisina kumira mumvura kana ethanol, chisingagadziki mu glycerin.
  3. Nicotinamide Mononucleotidepowderis iri nyore kunyora mumuromo, uye inogona kuparadzirwa kwazvo mumuviri, iyo yakawanda yemetabolite kana kuti prototype inokurumidza kubvisa kubva mumuti. Nicotinamide chikamu che coenzyme I uye coenzyme II inotora basa reHyidrogen inounzwa muhutano hwehutano hwemapfupa ekuputira, rinogona kukurudzira maitiro ekugadziriswa kwezvisikwa uye mishonga yemasabolism, kuchengetedza mhando dzemazuva ose (kunyanya ganda, chirwere chekudya uye nervous system) kuvimbika kune basa rinokosha.

Mukuwedzera, nicotinamide ine kudzivirira uye kurapwa kwemwoyo, chibato chekodhi basa uye anti-fast experimental arrhythmias, nicotinamide inogona kuwedzera zvakanyanya kutengesa kwemoyo uye atrioventricular block inokonzerwa ne verapamil.

Benefits yaNicotinamide Mononucleotide (NMN) powder (1094-61-7)

  • NMN Inowedzera Simba Metabolism - NAD + inobatsira kuputsa chikafu seshuga musimba.
  • Inokurudzira Healthy Brain uye Mwoyo Mwoyo.
  • Anti-Kuchembera DNA Kugadzirisa - NAD + inoshandiswa kugadzirisa tambo dzakaputsika dzeDNA.
  • SIRTUIN Activator - NAD + inodikanwa kuti hupenyu hwedu hurefu hushande.
  • NMN ndiro chigadziro chinoshandiswa naHarvard Scientists kuchinja zvimwe zviratidzo zvekukwegura kwemashuga mumakonzo akatanga rushandira kuNAD kuwedzera.
  • NMN kurapwa kunodzivirira kurwisana-kunokonzerwa nehutu hunokonzerwa nekuora kwehuropi
  • NMN Kuchengetedza Kununura kuora mwoyo kwepfungwa
  • Nicotinamide mononucleotide inhibits JNK kushandura kuderedza chirwere cheAlzheimer
  • NMN inogona kudzorera cognition mu AD maenzaniso rats

Yakakurudzirwa Nicotinamide Mononucleotide (NMN) powder (1094-61-7) Dosage

Iko inowanikwa yakawanda inonzi Nicotinamide Mononucleotide powder iri kupi pakati pe250 - 1500 mg pazuva.

NMN inokurumidza kukurumidza uye ine hafu yehupenyu hupenyu, saka kuchengetedza NAD + mazinga akakwirira kwemazuva akawanda sezvinobvira zvinokurudzirwa kutora imwe 125 mg capsule pakumuka uye imwe masikati kana uchitora 250 mg pazuva.

Zvikanganiso yaNicotinamide Mononucleotide (NMN) powder (1094-61-7)

Nepo Nicotinamide mononucleotide (NMN) poda iri nyowani nyowani uye kutsvagisa kuri kuenderera, zvidzidzo zvakaitwa kusvika parizvino zvakaratidza kuti yakachengeteka uye haina chepfu.

Zvimwe zvikanganiso hazviwanzovi, asi kunhuwa, chizuru, kutuka, uye kushungurudzwa kwakave zvataurwa kune dzimwe nguva.

 

References
  1. Nina Klimova, Tibor Kristian. Mazhinji-akanangwa Mhedzisiro yeNicotinamide Mononucleotide paBongo Bioenergetic Metabolism. Neurochem Res. 2019 Oct; 44 (10): 2280-2287. doi: 10.1007 / s11064-019-02729-0.PMID: 30661231.
  2. Aaron N Long, Katrina Owens, Anna E Schlappal, Tibor Kristian, Paul S Fishman, Rosemary A Schuh. Mhedzisiro yeNicotinamide mononucleotide pahuropi mitochondrial yekufema kushomeka mune yeAlzheimer's chirwere-inoenderana murine modhi. BMM Neurol. 2015 Mar 1; 15: 19. doi: 10.1186 / s12883-015-0272-x.PMID: 25884176.
  3. Ji H Park, Aaron Long, Katrina Owens, Tibor Kristian. Nicotinamide mononucleotide inhibits post-ischemic NAD (+) kudzikisira uye zvinoshamisa inovandudza kukuvara kwehuropi zvichitevera hutachiona hwepasi rose ischemia Neurobiol Dis. 2016 Mbudzi; 95: 102-10. doi: 10.1016 / j.nbd.2016.07.018. Epub 2016 Jul 15. PMID: 27425894, PMCID: PMC558024.
  4. Junichiro Irie, Hiroshi Itoh. Kukwegura uye homeostasis. Zera-zvinosangana nezvirwere uye kiriniki kushandiswa kweNMN (Nicotinamide Mononucleotide). Kliniki Calcium. 2017; 27 (7): 983-990. PMID: 28649105.
  5. Golam Mezbah Uddin, Neil A Youngson, Bronte M Doyle, David A Sinclair, Margaret J Morris. Nicotinamide mononucleotide (NMN) yekuwedzera inosimudzira kukanganisa kwehukama hwehukama mumakonzo: kuenzanisa nekurovedza muviri. Sci Rep. 2017 Nov 8; 7 (1): 15063. doi: 10.1038 / s41598-017-14866-z. PMID: 29118320, PMCID: PMC5678092.
  6. Zvazvino Zvekudzivirira-Kukwegura Zvinodhaka: Nicotinamide Mononucleotide (NMN)