NADH 2Na (606-68-8)

March 15, 2020

NADH chimiro chenicotinamide adenine dinucleotide (NAD) enzyme, inoshanda coenzyme fomu yekomboni uye vhitamini B3 ……….

 


Mamiriro: MuMitambo Yokugadzira
Synthesized and Customized Available
Unyanzvi: 1277kg / mwedzi

NADH 2Na (606-68-8) vhidhiyo

Beta-Nicotinamide adenine dinucleotide disodium munyu (NADH 2Na) Mafananidzo

Product Name Beta-Nicotinamide adenine dinucleotide disodium munyu (NADH 2Na)
Kemikari Name NADH (disodium munyu); Disodium nicotinamide adenine dinucleotide; eta-d-ribofuranosyl-3-pyridinecarboxamide, disodiumsalt; beta-NADH Disodium Munyu; Nicotinamide adenine dinucleotide, yakaderedzwa;
CAS Number 606-68-8
InChIKey QRGNQKGQENGQSE-WUEGHLCSSA-L
kunyemwerera C1C=CN(C=C1C(=O)N)C2C(C(C(O2)COP(=O)([O-])OP(=O)([O-])OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O.[Na+].[Na+]
Molecular Formula C21H27N7Na2O14P2
Molecular Weight 709.4
Monoisotopic Mass 709.088661 g / mol
Melting Point 140-142 ° C
ruvara Yero
SKuchengetedza temp 2-8 ° C
Solubility H2O: 50 mg / mL, yakajeka kusvika kune yakajeka, yero
kunyoresa Mushonga; zvekudya uye zvinovaka muviri

 

Chii chinonzi Beta-Nicotinamide adenine dinucleotide disodium munyu (NADH 2Na)?

NADH chimiro chenicotinamide adenine dinucleotide (NAD) enzyme, inoshanda coenzyme fomu yekomboni uye vhitamini B3. NADH (b-Nicotinamide adenine dinucleotide) Disodium Munyu, yakaderedzwa, inozivikanwawo seNicotinamide adenine dinucleotide, inonzi coenzyme mune redox reaction. Iwo mashandiro ayo seanogadziridza emagetsi mupi mune zvinokanganisa maitiro zvinosanganisira glycolysis, β-oxidation uye iyo citric acid kutenderera (Krebs kutenderera, TCA kutenderera). NADH disodium munyu inobatanidzwawo mumasero ekuratidzira zviitiko, semuenzaniso se substrate ye poly (ADP-ribose) polymerases (PARPs) panguva yeDNA kukuvara mhinduro Sezvo disodium munyu weNADH, inoshandiswa mukudya uye zvinovaka muviri zvekurapa chirwere chePasinson, chisingaperi kuneta chirwere, chirwere cheAlzheimer uye chirwere chemoyo.

 

Beta-Nicotinamide adenine dinucleotide disodium munyu (NADH 2Na) zvakanaka

Se coenzyme ye oxidoreductases, NADH disodium munyu inoita basa rakakosha mukugadzirwa kwesimba kwemuviri.

- NADH disodium munyu inogona kutungamira kujekesa kwepfungwa, kusvinura, kuisa pfungwa, uye ndangariro. Inogona kuwedzera kuchenjera kwepfungwa uye inogona kuwedzera manzwiro. Inogona kuwedzera masimba esimba mumuviri uye nekuvandudza metabolism, simba rehuropi uye kutsungirira.

- Batsira vanhu vane kliniki yekuora mwoyo, kuwedzera kweropa kana cholesterol yakawanda;

- Kuvandudza mitambo;

- Kunonoka kukwegura uye chengetedza kutendeseka kwemasero etsinga kutsigira system yemitsipa;

- Anogona kurapa chirwere chaParkinson, kunatsiridza mashandiro emaurotransmitter muuropi hwevarwere vane chirwere chePasinson, kuderedza hurema hwepanyama uye zvinodiwa nezvinodhaka;

- Bata chisingaperi kuneta chirwere (CFS), chirwere cheAlzheimer uye chirwere chemwoyo;

- Dzivirira kubva kumhedzisiro yemushonga weAIDS unonzi zidovudine (AZT);

- Rwisana nezvinokanganisa doro pachiropa;

- Kuneta kukuru

 

Beta-Nicotinamide adenine dinucleotide disodium munyu (NADH 2Na) madhara:

Parizvino, NADH disodium munyu inoita senge yakachengeteka kuvanhu vazhinji kana ichishandiswa zvakakodzera uye kwenguva pfupi, kusvika kumavhiki gumi nemaviri. Vazhinji vanhu havawani chero zvazvaitika zvinorwadza kana vachitora huwandu hwakakurudzirwa zuva rega rega, riri 12 mg.

Nekudaro, hapana dhata rakakwana pamusoro pekushandiswa kweNADH disodium munyu panguva yekuzvitakura uye kuyamwisa., Saka ivo vanofanirwa kugara parutivi rwakachengeteka vadzivise kushandiswa.

 

Dheuteronomio:

  • Birkmayer JG, Vrecko C, Volc D, Birkmayer W. Nicotinamide adenine dinucleotide (NADH) - nzira nyowani yekurapa kuchirwere cheParkinson. Kufananidza kwekutaura uye kweparenteral application. Acta Neurol Scand Suppl 1993; 146: 32-5.
  • Budavari S, ed. Iyo Merck Index. 12th ed. Whitehouse Chiteshi, NJ: Merck & Co, Inc., 1996.
  • Bushehri N, Jarrell ST, Lieberman S, et al. Oral yakaderedzwa B-nicotinamide adenine dinucleotide (NADH) inokanganisa kuwedzera kweropa, lipid peroxidation, uye lipid chimiro mune hypertensive makonzo (SHR). Geriatr Nephrol Urol 1998; 8: 95-100.
  • Bushehri N, Jarrell ST, Lieberman S, et al. Oral yakaderedzwa B-nicotinamide adenine dinucleotide (NADH) inokanganisa kuwedzera kweropa, lipid peroxidation, uye lipid chimiro mune hypertensive makonzo (SHR). Geriatr Nephrol Urol 1998; 8: 95-100.
  • Castro-Marrero J, Cordero MD, Segundo MJ, et al. Ko pamuromo coenzyme Q10 kusanganisa NADH kuwedzeredza kupera simba uye biochemical parameter mune chisingaperi chekuneta syndrome? Antioxid Redox Signal 2015; 22 (8): 679-85.
  • Dizdar N, Kagedal B, Lindvall B. Kurapa kwechirwere chePasinson neNADH. Acta Neurol Scand 1994; 90: 345-7.