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Nicotinamide riboside chloride (NR-CL) (23111-00-4)

Nicotinamide riboside (NR) ingori ichangobva kuwanikwa nicotinamide adenine dinucleotide (NAD + )amberi vhitamini. The …….


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Nicotinamide riboside chloride (NR-CL) (23111-00-4) Specifications

Product Name Nicotinamide riboside chloride (NR-CL) (23111-00-4)
Kemikari Name NRC; 3-Carbamoyl-1-beta-D-ribofuranosylpyridinium chloride; Nicotinamide ribose chloride; 3-Carbamoyl-1- (β-D-ribofuranosyl) pyridinium chloride; 3-carbamoyl-1 - ((2R, 3R, 4S, 5R) -3,4-dihydroxy-5- (hydroxymethyl) tetrahydrofuran-2-yl) pyridin-1-ium chloride; Nicotinamide BD Riboside Chloride (WX900111); NR-CL;
CAS Number 23111-00-4
InChIKey YABIFCKURFRPPO-IVOJBTPCSA-N
kunyemwerera C1 = CC (= C [N +] (= C1) C2C (C (C (O2) CO) O) O) C (= O) N. [Cl-]
Molecular Formula C11H15ClN2O5
Molecular Weight 290.7002
Monoisotopic Mass 290.066949 g / mol
Melting Point N / A
ruvara chena
Storage temp -20 ° C Freezer
kunyoresa zvekudya zvinowedzera, munda wemishonga

Chii Nicotinamide riboside chloride(NR-CL)?

Nicotinamide riboside (NR) ingori ichangobva kuwanikwa nicotinamide adenine dinucleotide (NAD + )amberi vhitamini. Chimiro cheKristalline cheNR chloride chinonzi NIAGEN, chiri chimiro chinogadzira nicotinamide riboside uye kunobva kwainobva iyo nicotinamide muchimiro cheiyo nicotinic acid inogona kuve bioavava uye inowanzoonekwa yakachengeteka (GRAS). NR chloride ndiyo nyaya yezvinyorwa zviviri zvitsva zvemhando yekudya, izvo zvinonyanya kushandiswa muzvikafu zvinowedzera.

Nicotinamide Riboside Chloride chimwe chinhu chakasikwa chinowanikwa mumukaka. Iyo inonyatsoenderana ne niacin uye mamwe marudzi evhitamini B3. Dzimwe tsvakiridzo dzakaona kuti Nicotinamide Riboside Chloride ine humwe hunhu hunoshamisa hunogona kukurudzira metabolism kubatsira kupisa macalorie akawanda uye kudzivirira kuwedzera uremu. Pamusoro pekudzikira uremu, zvinobatsirawo kukwidziridza tsandanyama kuita, kuwedzera simba remagetsi, uye kuderedza njodzi dzechirwere cheshuga.

Zvakare, kutsvakwa kwakaitwa muvanhu kwakaratidza kuti zvese zveNicotinamide Riboside Chloride zvinosimudza nhanho dzeNAD, + izvo zvinobatsira kukonzeresa mamwe mamiriro ane hukama nezera, kunyange zvichikurumidza kuziva kuti zvichanyatsoita sei.

kubatsira Nicotinamide riboside chloride(NR-CL)

Nicotinamide riboside chloride chimiro chinogadzira nicotinamide riboside, zvarinobatsira / basa rakafanana nicotinamide riboside. Inotora chikamu mumetabolism mumuviri, inogona kushandiswa kudzivirira pellagra kana imwe niacin defection chirwere uye kuderedza cholesterol uye triglycerides muropa. Izvo zvinoshandiswawo kudzikisa njodzi yekurohwa kwemoyo muvanhu vane cholesterol yakakwira vakatove nekurova kwemoyo. Dzimwe nguva inoshandiswa kurapa coronary artery chirwere (atherosclerosis), chengetedza kuchengetedza uropi uye chiropa (chirwere chemoyo, chirwere cheshuga, chirwere cheAlzheimer's).

Kunze kwezvo, Nicotinamide riboside chloride inewo zvimwe zvakanaka muvanhu:

  • Kugaya chaipo uye kupinza mapuroteni nemafuta;
  • Batsira kushandura iyo yakakosha amino acid tryptophan mu niacin;
  • Kuderedza kurutsa, uye kuderedza mhedzisiro yekutora antidepressants nekuda kwemuromo wakaoma uye kunetseka kurapa;
  • Kurudzira nicic acid synthesis uye kudzivirira kukwegura kwehutachiona uye nhengo, nekudaro kuzadzisa chinangwa chekunonoka kukwegura;
  • Kunonoka musono mutsipa spasm, kupora mitezo uye ruoko uye tsoka etsoka;
  • Kurapa kweiyogengenism hypometabolism uye kuwedzerwa kwemetabolism;
  • Kudzivirira uye kurapwa kwevhitamini B6 kushomeka;
  • Kurapa kwe carpal tunaki syndrome;
  • Inobatsira kuderedza uremu uye kusimbisa tsandanyama basa.
  • Kuvandudza kusasimba kwemuviri kumasero ekenza
  • Dzivirira kurasikirwa kwekunzwa
  • Ko ndeye diuretiki yepanyama.
  • Kutora yakakura madosi kunogona kudzoreredza zvinodhaka uye kuve neakanaka detoxization athari.
  • Kuvandudza kushanda kwemaseru epermermal, pamwe nemabasa emamwe maseru mumuviri wemunhu, kuti ganda rirambe richiratidzika.

Nicotinamide riboside chloride(NR-CL) shandisa

Nekuti Nicotinamide riboside chloride ine zvimiti zvinobatsira zvekurapa, inowanzoshandiswa mune zvekudya zvinowedzera, mushonga uye munda wekudya.

Dheuteronomio:

  • Conze D, Brenner C, Kruger CL. Kuchengetedza uye Metabolism yeNguva refu Yekutonga kweNIAGEN (Nicotinamide Riboside Chloride) muRandomized, Double-Blind, Placebo-inodzorwa Clinical Trial yeVatano Vakawanda Vanorema. Sci Rep. 2019 Jul 5; 9 (1): 9772. doi: 10.1038 / s41598-019-46120-z. PMID: 31278280 PMCID: PMC6611812.
  • Bogan, KL, Brenner, C. (2008). "Nicotinic acid, nicotinamide, uye nicotinamide riboside: kuongororwa kwemolesi yevhitamini yeNAD + mune hutano hwevanhu". Annu. Rev. Nutr. 28: 115–130. Doi: 10.1146 / annurev.nutr.28.061807.155443. PMID 18429699.
  • Chi Y, Sauve AA (Mbudzi 2013). "Nicotinamide riboside, inoteedzera zvinovaka zvinovaka muzvikafu, ivhitamini B3 ine mhedzisiro yesimba metabolism uye neuroprotection". Curr Opin Clin Nutr Metab Kutarisirwa. 16 (6): 657-61. doi: 10.1097 / MCO.0b013e32836510c0. PMID 24071780.

KUGADZIRIRA UYE KUDZIDZA:

Ichi Chinyorwa Kutengeswa Kwekutsvagisa Chete Chete. Mitemo Yekutengesa Nyorera. Kwete Yekushandiswa Kwevanhu, kana Kurapa, Veterinary, kana Kushandisa Kweimba.


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Nicotinamide riboside chloride (NR-CL) (23111-00-4) vhidhiyo

References & chigadzirwa mhizha