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Raw Flibanserin HCL powder (147359-76-0)

Raw Flibanserin hydrochloride powder, inotengeswa pasi pezita rekutengeserana Addyi, imishonga inogamuchirwa kurapa ...


Mamiriro: MuMitambo Yokugadzira
Unit: 25kg / Drum
Unyanzvi: 1250kg / mwedzi

tsananguro

Raw Flibanserin HCL powder (147359-76-0) video

Raw Flibanserin HCL powder (147359-76-0) Specifications

Product Name Flibanserin hydrochloride powder
Kemikari Name UNII-96XTC36K1B, 96XTC36K1B
muchiso Name Addyi
Kirasi yeMishonga Multifunctional serotonin agonist antiagonist (MSAA)
CAS Number 147359-76-0
InChIKey XGAGFLQFMFCIHZ-UHFFFAOYSA-N
Molecular Formula C20H22ClF3N4O
Molecular Wsere 426.8630896
Monoisotopic Mass 426.143 g / mol
Kunyorera Point > 225 ° C (dec.)
Freezing Point Hapana zuva rawanikwa
Biological Half-Life 11 maawa
ruvara Yakachena yakasimba
Skukodzera DMSO (Zvishoma), Methanol (Zvishoma)
Storage Temperature Room Temperature Temperature
APane Yakagadzirirwa kurapwa kwekunetseka kwepabonde chirwere chechida pakati pevakadzi.

Raw Flibanserin HCL powder (147359-76-0) Tsanangudzo

Flibanserin hydrochloride ndiyo yekutanga mishonga inobvumidzwa kuti iite chisingaiti chepabonde chishuvo chekuita zvepabonde (HSDD) mumadzimai ekutanga anmenopausal neDFA muna August 2015. Yakatanga kusimbiswa semishonga inopesana nemishonga naBoehringer Ingelheim, asi yakaratidza kusakwanisa kwekuita mumiedzo uye yakawedzerwa mberi seye hypoactive kugadzirisa chirwere chepabonde neSprout Pharmaceuticals. Flibanserin's mechanism of action inonzi inofanirwa nehukama hwakasimba hwe 5-HTA1 uye 5-HTA2 receptors, kuratidza mabasa agonist pa 5-HTA1 uye mupikisi pa 5-HTA2, zvichiita kuti kuderedzwa kwe serotonin muuropi pamwe nemigumisiro pakuwedzera norepinephrine uye dopamine neurotransmitters.

Flibanserin hydrochloride powder (147359-76-0) Mechanism of Action

Flibanserin hydrochloride inoshanda pamatatu emakemikari anokosha anokosha: dopamine, norepinephrine, uye serotonin. Aya makemikari mapurogiramu eurotransmitters. Ivo vane basa rekutumira zviratidzo pakati peuropi uye zvimwe zvikamu zvemuviri kuburikidza nehutano hwemitsipa.

Dopamine uye norepinephrine vanobatanidzwa mune zvepabonde. Zvisinei, serotonin inobatsira kugadzirisa zvepabonde uye inogona kuderedza zvepabonde motokari. Zvinofungidzirwa kuti kana aya makemikari asingakoshi - kana dopamine uye norepinephrin mazinga ari pasi nepakati uye / kana serotonin mazinga akakwirira-mukadzi anganzwa kunzwa zvisingaiti zvepabonde.

Flibanserin hydrochloride inoshanda nekuwedzera mazinga e dopamine uye norepinephrine nekuderedza mazinga e serotonin. Nenzira iyi, makemikari anobatsira kukurudzira chido chepabonde ichiwedzerwa uye chimwe chinogona kudzivisa chido chakaderera.

Kushandiswa kweRaw Flibanserin HCL powder (147359-76-0)

Flibanserin hydrochloride inonzi 5-HT1A agonist uye 5-HT2A anopikisa iyo yakagadzirirwa kurapwa kwechishuvo chepabonde chishuvo chepabonde kune vakadzi (1,2).

Yakakurudzirwa Raw Flibanserin HCL powder (147359-76-0) Dosage

100 mg muromo kamwechete pazuva pazuva

Nguva yekurapa: Uyu mushonga unofanirwa kubviswa mushure memasvondo e8 kana murwere asingatauri kuvandudzwa kwezviratidzo.

Mhinduro: Uyu mishonga hauratidzirwe kuti uwedzere kuita zvepabonde, uye hauratidzirwe mukurapwa mumadzimai ekuma postmenopausal kana mumarume.

Zvibereko zveFlibanserin hydrochloride powder (147359-76-0)

Zviitiko zvakaipa zvinowanzoonekwa pakati pevakadzi vachitora flibanserin. Zvizhinji zvezviitiko zvinotambudza zvaive zvinyoro kuenzanisa. Zviitiko zvinowanzoshushwa zvinosanganisa zvinosanganisira kuve nechezzinesi, kusuruvara, kunzwa kuneta, kurara, uye kunetseka kurara.

Kunwa doro panguva yeflibanserin kunogona kukonzera kukanganiswa kwepabonde kweropa (kuderera kweropa kunokonzera zviratidzo mushure mechikamu che 2 chewaini chakaitika mu17%).

KUGADZIRIRA UYE KUDZIDZA:

Ichi Chinyorwa Kutengeswa Kwekutsvagisa Chete Chete. Mitemo Yekutengesa Nyorera. Kwete Yekushandiswa Kwevanhu, kana Kurapa, Veterinary, kana Kushandisa Kweimba.