Dihydromyricetin (DHM) (27200-12-0)

March 9, 2020

Dihydromyricetin (kana DHM) chiumbwa chinobva muJapan Raisin Muti icho chave chishandiswa kwemazana emakore seanorwisa doro …….


Mamiriro: MuMitambo Yokugadzira
Synthesized and Customized Available
Unyanzvi: 1277kg / mwedzi

Dihydromyricetin (DHM) (27200-12-0) vhidhiyo

Dihydromyricetin Specifications

Product Name Dihydromyricetin (DHM)
Kemikari Name Ampelopsin
Ampeloptin
(+) - Dihydromyricetin
Brand Name N / A
Kirasi yeMishonga phytochemical, zvirevo zvinotaridzwa kubva kuChina mishonga yemishonga (TCM).
CAS Number 27200-12-0
InChIKey KJXSIXMJHKAJOD-LSDHHAIUSA-N
Molecular Formula C15H12O8
Molecular Wsere 320.25 g / mol
Monoisotopic Mass 320.053217 g / mol
Kubikira pfungwa 780.7 ± 60.0 ° C (Zvakafanotaurwa)
Freezing Point N / A
Biological Half-Life N / A
ruvara white to beige
Skukodzera DMSO: ≥5mg / mL (yakadziyirwa)
Storage Temperature <+ 8 ° C
APane 1. Inoshandiswa indasitiri yekupa zvekudya, dihydromyricetin poda inoshandiswa sezvigadzirwa;
2. Inoshandiswa mune chigadzirwa chehutano, dihydromyricetin poda inoshandiswa sezvinhu zvakagadzirwa kuti igadzire immune immune;
3. Inoshandiswa mumunda wemishonga, dihydromyricetin inobvisa hupfu hunoshandiswa semapiritsi kana mapiritsi ekurapa chirwere chekufema chetachiona nekuchengetedza chiropa.

Dihydromyricetin Nhoroondo

Dihydromyricetin (kana DHM) chiumbwa kubva muJapan Raisin Muti icho chave chishandiswa kwemazana emakore seanorwisa-dhivha yemakwenzi uye hangover kurapa muKorea uye Chinese mishonga yechivanhu. Ongororo dzichangobva kuitika dzinoratidza kuti DHM inogona kudzikisa doro rako reropa nekuchengetedza chiropa chako kubva mukukuvadzwa nechirwere.

DHM ndeye flavonoid inowanzo bviswa kubva kuVine Tea asi zvakare inogona kutorwa kubva kuhungwa rwemuti weHolvenia Dulcis. Uye chinonyanya kukosha ndechekuti Dihydromyricetin ine nhoroondo refu yekutorwa yakanyatsoitirwa kuti varape misoro nemhango.

Chii chinonzi Dihydromyricetin?

Dihydromyricetin, inozivikanwawo seAmpelopsin, ndeye flavanonol, mhando ye flavonoid. Inowanikwa muAmpelopsis marudzi japonica, megalophylla, uye grossedentata; Cercidiphyllum japonicum; Hovenia dulcis; Rhododendron cinnabarinum; mamwe marudzi ePini; uye mamwe marudzi eCedrus, pamwe muSalix sachalinensis.

Dihydromyricetin inobvisa poda, yakakosha inoshanda ndeye flavonoids. Iine mabasa ekuchera mahara radicals, antioxidants, antithrombotic, Tumor, anti-immune uye zvimwe zvinoshamisa mhedzisiro; Dihydromyricetin inokosha yakasarudzika flavonoid. Kuwedzera kune zvakajairika hunhu hwe flavonoid, ine zvakare kukwanisa kudzikisa doro muchetura, kudzivirira chinwiwa chinodhaka, mafuta echiropa, uye inhibit masero echiropa. Kupisa uye kuderedza chiitiko chechiropa chegomarara. Icho chigadzirwa chakanaka chekuchengetedza chiropa uye hangover.

Dihydromyricetin zvinobatsira

ANTI-HANGOVER ANOGONESA

DHM kubatsirwa kukuru ndeyekudzivirira uye kudzikisira kwemasango, kuchengetedza chiropa chako pamwe nehuropi. Izvi zvinowanikwa nekuwedzerwa kwedoro dehydrogenase (ADH) uye acetaldehyde dehydrogenase (ALDH), ayo ari main enzymes anotarisira kuputsa doro uye acetaldehyde mukati memuviri.

Acetaldehyde kunyanya ikemikari ine muchetura uye imwe yezvakanyanya kukonzera hangovers. Kana ma enzymes aya agadziridzwa, doro neacetaldehyde rinogona kuputswa nekukurumidza kupfuura zvakajairwa.

UPENYU HWAKANAKA

DHM ine akawanda masero ehutano hutano anozvikweretesa nekusimudzira hutano hwekuziva. Izvi zvinoitika nekuti DHM inosimudzira heme-oxygenase-1 (HO-1), enzyme inobatsira kudzikisira kweheme uye inoparadzira hutano hwemasimba. Dihydromyricetin inogonawo kukurudzira hutano hwechiropa.

Iyo imwe dihydromyricetin inobatsira

1) Dihydromyricetin inogona Kuchenesa zvakasununguka zvakasarudzika mumuviri uye antioxidation

2) Dihydromyricetin inogona Antibiotic Action

3) Dihydromyricetin inogona Kuchengetedza Chiropa: Dihydromyricetin ine yakasimba inhibitory chiitiko chekusimuka kwe ALT uye AST muropa Serum. Iyo inogona kuderedza iyo yakazara bilirubin mu seramu yeropa. Saka iine chiito chakasimba chekudzikisa aminotransferase uye jaundice.

4) Dihydromyricetin inogona Kuderedza uwandu hweshuga yeropa uye nemafuta eropa: Dihydromyricetin inogona kuderedza uwandu hwemafuta eropa muchirairo. Iyo inogona kuderedza kukuvadzwa kwemaseru echiropa kunokonzerwa nehuwandu hwemafuta eropa uye nekuvandudza kugona kwe antioxidation. Panguva imwecheteyo, inogona kuderedza huwandu hweshuga yakakwira yeropa.

5) Dihydromyricetin inogona Anti-kuzvimba

6) Dihydromyricetin inogona Anti-bundu: Dihydromyricetin inobvisa poda ine inoshanda kudzora cell kuwedzera proriferation kwemamwe tumor cell.

Dihydromyricetin mativi.

Pakazara pane angori mashoma zvidzidzo kusvika parizvino achitarisa paDHMs side athari profil uye kusvika pari zvino hapana matambudziko anonetsa ataurwa.

Iko kukurumidza kutsvaga paAmazon kucharatidza zviuru zvekuongorora. Kutsvaga kuburikidza navo, kune zvimwe zvirevo zvekusagadzikana mudumbu, kusvotwa, uye manyoka. Nekudaro, hapana vazhinji vatengi vanotaura izvi mhedzisiro.

Dihydromyricetin inoshandisa uye kushandisa

Zvishandiso:

  1. Dihydromyricetin poda inoshandiswa kuchengetedza chiropa;
  2. Dihydromyricetin poda inoshandiswa kugadzirisa mafuta eropa eropa mafuta;
  3. Dihydromyricetin poda ine mhedzisiro yekuvandudza kusadzivirirwa kwemuviri;
  4. Dihydromyricetin poda nebasa reantioxidant uye anti-cancer;
  5. Dihydromyricetin poda inoshandiswa kurwisa mabhakitiriya, kurapa kukosora, kurwadziwa uye kubvisa utsi hwepfu.
  6. Iyo dihydromyricetin ine yakavimbisa tarisiro yekuvandudza mukugadzirira kwezvinhu zvekuchengetedza-ganda kana zvinodhaka zvekudzivirira nekurapa kukuvara kweganda.

kunyoresa

  1. Inoshandiswa indasitiri yekupa zvekudya, dihydromyricetin poda inoshandiswa sezvinhu zvakagadzirwa;
  2. Inoshandiswa mune chigadzirwa chehutano, dihydromyricetin poda inoshandiswa sezvinhu zvakagadzirwa kuti igadzire kuchengetedzwa kwemuviri;
  3. Inoshandiswa mumunda wemishonga, dihydromyricetin inobvisa poda inoshandiswa semapiritsi kana mapiritsi ekurapa chirwere chekufema chetachiona nekuchengetedza chiropa.

Dihydromyricetin tsvakurudzo in Anti-Kenza

Muchokwadi, kune kumwe kutsvakisisa kunotsigira kunoratidza kuti dihydromyricetin ine mukana wekubatsira nemamiriro asiri-echinwiwa mamiriro anonzi Hepatocellular carcinoma (HCC). HCC mamiriro ezvinhu anoratidza chimwe chakanyanya kusagadzikana kwekushomeka uye kufa kwepasi rese, uye inopa predompeant subtype yepakutanga cancer cancer. Sezvo DHM inoratidza inokwanisa kudzivirira pachiropa (chiri hepatprotective) izvo zvabuda zvinoratidza kuti zvakanyanyisa kudzivirira cell kuwedzera uye kukonzera cell apoptosis mumitsetse yeHCC cell, zvichiratidza kuti DHM inovimbisa inomiririra kurapwa kweHCC.

Reference:

Dihydromyricetin inoderedza doxorubicin-indized cardiotoxicity nekuvhiringidza NLRP3 inflammasome kuburikidza nekutanga kweSIRT1. Zuva Z, Lu W, Lin N, Lin H, Zhang J, Ni T, Meng L, Zhang C, Guo H. Biochem Pharmacol. 2020 Feb 26: 113888. doi: 10.1016 / j.bcp.2020.113888. [Epub pamberi pekudhinda]

Metabolomics yeiyo Inochengetedza Mhedzisiro yeAmpelopsis grossedentata uye Yayo Yakakura Active Compound Dihydromyricetin pane Chiropa chePamusoro-Fat Diet Hamster. Fan L, Qu X, Yi T, Peng Y, Jiang M, Miao J, Xiao P. Evid Yakavakirwa Complement Alternat Med. 2020 Jan 28; 2020: 3472578. doi: 10.1155 / 2020/3472578. eCollection 2020.

Mirairo yekusaina nzira nzira neAmpelopsin (Dihydromyricetin) mumakanzuru akasiyana: kuongorora nzira huru nemigwagwa isingafambi. Fayyaz S, Qureshi MZ, Alhewairini SS, Avnioglu S, Attar R, Sabitaliyevich UY, Buha A, Salahuddin H, Adylova A, Tahir F, Pawlak-Adamska E. Cell Mol Biol (Noisy-le-grand). 2019 Sep 30; 65 (7): 15-20.

Golgi kuvandudza uye kusunga protein 65 kudzika kunodiwa kune anti-cancer kenza ye dihydromyricetin pamasero ekenza yemunhu ovarian. Wang F, Chen X, Yuan D, Yi Y, Luo Y.

PloS Imwe. 2019 Oct 26; 14 (11): e0225450. doi: 10.1371 / journal.pone.0225450. eCollection 2019.

KUGADZIRIRA UYE KUDZIDZA:

Ichi Chinyorwa Kutengeswa Kwekutsvagisa Chete Chete. Mitemo Yekutengesa Nyorera. Kwete Yekushandiswa Kwevanhu, kana Kurapa, Veterinary, kana Kushandisa Kweimba.