Raw Pterostilbene powder (537-42-8)

December 28, 2018
SKU: 537-42-8
5.00 kupererwa ne 5 maererano ne 1 kasitoma Rating

Pterostilbene powder is antioxidant iyo inonyanya iri mu blueberries, mazambiringa uye heartwood yeguru sandalwood. Pterostilbene .......


Mamiriro: MuMitambo Yokugadzira
Unit: 25kg / Drum
Unyanzvi: 1180kg / mwedzi

Raw Pterostilbene powder (537-42-8) video

Raw Pterostilbene powder (537-42-8)

Raw Pterostilbene powder ye naturally-yakagadzirwa stilbenoid yakarongeka ne resveratrol, ine simba rinogona kupikisa antioxidant, anti-inflammatory, pro-apoptotic, antineoplastic uye cytoprotective mabasa. Pamusoro pehutungamiri, Raw Pterostilbene powder inoshandisa basa rayo rinopisa-oxidant kuburikidza nekuputsa maitiro eoksijeni anogadzirisa (ROS), nokudaro kudzivirira kushungurudzika kweiyo oxyidative uye ROS-yakaita sero rinoparadza. Inogonawo kuita kuti nyukliya inokonzerwa ne-2-yakabatana nechokuita 2 (Nrf2) -gadziriswa nzira uye inowedzera kutaura kwemarudzi akasiyana-siyana e-antioxidant enzymes, akadai sa superoxide dismutase (SOD). Mukuwedzera, Raw Pterostilbene powder inokwanisa kudzivisa kupisa nekuderedza kutaura kwevamwe vapikisi vanopesana, zvakadai se interleukin (IL) 1beta, tumor necrosis factor alpha (TNF-a), inducible nitric oxide synthase (iNOS), cyclooxygenases (COX) , uye nyukireya factor kappa B (NF-kB). Inodzivisawo kana kudzivirira kushandiswa kwemaitiro akawanda ekucherechedza maitiro anobatanidzwa mucarcinogenesis, uye inowedzera kutaura kwezvipembenene zvakasiyana-siyana zvinopesana nejeni apo kuderera kwekutaura kwechimwe chirwere chinokurudzira majeni. Inobatanidzawo zvakananga apoptosis mumarara masero.

Raw Pterostilbene powder (537-42-8) Specifications

Product Name Raw Pterostilbene powder
Kemikari Name Raw Pterostilbene powder;

4-(3,5-Dimethoxystyryl)phenol; (E)-4-(3,5-dimethoxystyryl)phenol; 3′,5′-Dimethoxy-4-stilbenol

muchiso Name Kwete deta yekuwanikwa
Kirasi yeMishonga Kwete deta yekuwanikwa
CAS Number 537-42-8
InChIKey VLEUZFDZJKSGMX-ONEGZZNKSA-N
Molecular Formula C16H16O3
Molecular Wsere 256.301 g / mol
Monoisotopic Mass 256.11 g / mol
Misa chaiye 256.11 g / mol
SMILES CC1=C(OC2=NC3=C(CCCC3)C(=C12)NC(=O)CN4CCCC4=O)C
Biological Half-Life Kwete deta yekuwanikwa
ruvara White powder
Skukodzera Kwete deta yekuwanikwa
Storage Temperature Chengeta pachitonho chemukati
APane Stilbenoid yakasikwa-chaiyo yakagadzikana yakabatana ne resveratrol

Raw Pterostilbene powder (537-42-8) Tsanangudzo

Pterostilbene iyi inonzi methylated stilbene molecule inogadziriswa nehutano ku resveratrol, musiyano chete uri maviri ma-methoxy mazana pecosostilbene molecule inoshandura mapoka e hydroxy pa resveratrol molecule. Kunyange zvazvo zvizhinji zvezviito zveizvi zviviri zvakafanana, pterostilbene inoratidzika kunge yakanyatsonyatsonyanya kufanana nekutevedza kwemuromo uye inogona kuva yakanyanya antioxidant uye antiticancer molecule.

Chidzidzo chimwe bedzi chakaongorora pterostilbene powder kuvanhu. Yakawedzerwa kuwedzera kweLDL-cholesterol uye kuenderera mberi kumazinga ekuderera eHCDL kuvanhu vane high cholesterol maitiro avo vakatora 100 kana 250 mg pazuva. Zvakanga zvisina kujeka kana chirwere chepasi chichitungamirira kuderedza kuderedzwa kweropa, asi kuderedzwa kweboka iro rakatora dhigiri rakakwirira raiva rakasimba.

Pterostilbene powder (537-42-8) Mechanism of Action

Pterostilbene kurwisana nehutachiona hwekushushikana nekubatanidza kubatanidza antioxidant enzymes. Inowedzera superoxide dismutase 1 (SOD1) uye peroxiredoxin-4 (PRDX4), iyo inosungirirwa kumagadzirirwo eoksijeni akasiyana. Vatsvakurudzi vakaona izvi zvichiitika mumasero eziso revanhu, zvichiratidza kuti pterostilbene inogona kudzivirira kubva kune zvinokonzera kukanganisa. Kunze, Pterostilbene inoshandisawo SIRT1 nzira yekucherechedza iyo inodzivirira kusangana kwemasero. Iyi nzira inowedzera kutaura kweP53, puroteni inodzivirira DNA uye inodzivirira kuchinja kunogona kutungamirira kenza.

Kunyange zvazvo SIRT1 inogona kudzivirira pane zvimwe zvekuderera uye kukuvadza kunoitika patinokura. Zvisinei, pterostilbene haisi mapiritsi emashiripiti pakurwara.

Ongororo dzakawanda dzakaratidza kuti pterostilbene inoderedza kuputika kunoenderana nekenza necrosis factor-alpha (TNF-alpha). Kuora mwoyo kunokonzera kupisa; pterostilbene inogona kuvhiringidza TNF-alpha uye interleukin-1b (IL-1b) nekuderedza kushandiswa kweiyo oxygen marudzi.

Pterostilbene inodzivirirawo kushungurudzika mukati memagetsi emagetsi anonzi endoplasmic reticulum, kana ER. Mune rumwe ruzivo, apo masero kubva pamakumbo emidziyo yeropa akaiswa pachena pterostilbene, ER wavo haana kugamuchira zviratidzo zvekuvhiringidza, uye havana kupera.

Pterostilbene ine ruzivo rwakakura rwekugona kurwisa kenza nzira. Inogona kuchengetedza masero ane utano uye inokanganisa masero ane kenza. Mu glioma (uropi kana kenza yemusana) masero, pterostilbene yakaderera Bcl-2 uye yakawedzera Bhax; idzi kuchinja kunowedzera sero "kuzviuraya" zviratidzo uye zvinokonzera glioma masero kuti afe.

Pterostilbene inoratidzika kuti inosarudzira nzvimbo inonzi hippocampus muuropi. Ikoko, inowedzera huropi-yakagadzirirwa neurotrophic factor (BDNF), mitogen-activated protein kinases (MAPK), uye mhinduro yeCAMP inosunga mapuroteni (CREB). Aya mapuroteni matatu anobatsira neuroni kukura, kuwedzera, uye kupindura kune zvakapoteredza. SNRI zvinodzvinyirira zvinowanzotarisa nzira idzi zvakare. Uyewo mumukoko, pterostilbene inowedzera puroteni inonzi Nrf2, iyo inowedzerawo kutaura kwe antioxidant mapuroteni.

Iko monoamine oxidases, MAOs, iine enzymes inoparadza maurotransmitter muuropi. Chimwe chezvinokonzerwa nemakemikari, MAO-B, kusarudza kusarura dopamine; semugumisiro, zvinodhaka zvinodzivisa MAO-B kuwedzera dopamine muuropi. Maererano neakawanikwa munguva pfupi yapfuura, pterostilbene inhibits MAO-B basa uye, nokudaro, inowedzera inowanika dopamine.

Pterostilbene powder inogona kudzivirira chirwere cheAlzheimer nekuchengetedza uropi kubva kune beta-amyloid (Aβ). Nzira chaiyo haina kuzivikanwa, asi inoratidzika kusanganisira PI3K uye Akt, mapurotini maviri anotsigira chiyeuchidzo, kudzidza, uye neuron kukura.

shandisa yePterostilbene powder (537-42-8)

  • Chirwere cheAlzheimer
  • Atherosclerosis
  • chirwere cheshuga
  • High blood pressure
  • High cholesterol
  • Insulin kushorwa

Yakakurudzirwa Pterostilbene powder (537-42-8) Dosage

Mune vanhu, mahara kusvika ku 250 mg pazuva anonzi akachengeteka. Mizinga yakakwirira yakadai seyiyi yakaratidzwa kuderedza kushanda kweropa uye kukurudzira kuora kwekurema. LDL cholesterol yakakura zvakanyanya zvakare, asi izvi zvakakanganiswa zvachose nekuwedzerwa kwechibereko chemazambiringa.

Mune mhuka, maitiro akawanda ezasi akave ane njere dzinonzwisisika. Pakati pe1 uye 2 mg pamakilogiramu ekurema kwezuva nezuva kunoderedza kushungurudzika mumakonzo. Kushandisa chimiro chakafanana-chiyero chakaenzana pakati pemakonzo nevanhu, chiyero chekutanga (mumug) kune munhu chichati uremu hwavo mu kg yakakamurwa ne12.3. Izvozvo zvinoshanda kune:

4.6 mg / zuva re 125 lb munhu

5.5 mg / zuva re 150 lb munhu

6.5 mg / zuva re 175 lb munhu

7.3 mg / zuva re 200 lb munhu

Kana iwe uri kutora pterostilbene powder nokuda kwekubatsira kwaanoziva, iwe unogona kuda kutanga nehana yakaderera zvikuru. Zvisinei, zviitiko izvi zvakaderera zvakangoti zvave zvichengetwa mumakonzo kusvika ikozvino, uye vanhu vanogona kunyatsonakidzwa nekugutsikana kwepamusoro pamitambo yakakwirira.

Kubatsira kwePterostilbene powder (537-42-8)

Pterostilbene powder is antioxidant iyo inonyanya kuwanikwa, iyo ine chemopreventive, antiinflammatory, antidiabetic, antidyslipidemic, antiatherosclerotic uye neuroprotective madhara. Kunze kwazvo, inewo mamwe mazano sezasi:

  • Inobatsira kurwisana nekenza
  • Inovandudza cognition uye inodzivirira kero yekufa muuropi
  • Inoderedza ropa Sugar
  • Inoderedza Kupisa
  • Inodzivirira Chiropa
  • Ngadzivirire Mwoyo
  • May Sotsigira Kurasikirwa Kwemafuro
  • Inodzivirira Maziso
  • May Dai Kuwedzera Maitiro
  • Inoderedza ropa

KUGADZIRIRA UYE KUDZIDZA:

Ichi Chinyorwa Kutengeswa Kwekutsvagisa Chete Chete. Mitemo Yekutengesa Nyorera. Kwete Yekushandiswa Kwevanhu, kana Kurapa, Veterinary, kana Kushandisa Kweimba.